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pbmx ah 40
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Non Receptor Tyrosine Kinase BMX PubMed Central (PMC)
Apr 12, 2011 · As BMX is a kinase, we validated the activation of BMX in GSCs by measuring its specific phosphorylation on Tyr 40 [pBMX Kimmelman AC, Ying H, Nabioullin R, Ponugoti AH, Wiedemeyer R, Stegh AH, Bradner JE, Ligon KL, Brennan C, et al. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science.
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Operating margins increased in the fourth quarter as reductions in unit costs offset lower gold prices. A total of 323,000 ounces of gold were sold in the quarter, at an average realised cash price of $792/oz, down from $847/ oz in the three months to September.
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BMX Negatively Regulates BAK Function, Thereby Increasing
BMX has been implicated in the development of prostate cancer (22, 40), where elevated levels may compensate for androgen deprivation (28, 41). Furthermore, a requirement of BMX for glioblastoma stem cell survival has been identified , as well as a role for BMX in the pathogenesis of bladder cancer .
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Direct contact with perivascular tumor cells enhances
Phospho BMX staining of ECs in the xenograft tumors was detected in a population of vessels, consistent with BMX eion in vessels of arterial origin [39, 40]. These data suggest that ECs interact with tumor cells in the perivascular niche through an RGD peptide binding integrin and that this interaction promotes BMX and p130CAS activation
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Tanning predicts bone mass but not structure in adolescent
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